Process Development Scientist, Downstream
Company: New England Biolabs
Posted on: May 14, 2022
New England Biolabs (NEB) is seeking a driven Process
Development (PD) Scientist for an MSAT role within our expanding,
multidisciplinary PD group. The person in this position will work
closely with existing PD resources to establish scalable processing
solutions for our diverse product portfolio. Within this
fast-paced, dynamic, and collaborative work environment the
successful candidate will elevate the manufacturing of high-quality
reagents across multiple facilities.
Conceive, plan, and execute technical projects at bench and pilot
scales in the areas of cell lysis and clarification with particular
goals to develop and characterize unit operations.
Investigate multiple methods of cell lysis (e.g. conventional
high-pressure homogenization, high shear microfluidization) and
clarification (e.g. tubular bowl and disc stack centrifuge, polymer
induced flocculation, depth filtration, tangential flow
Establish techniques and metrics for process analysis including
turbidity, viscosity, particle size, product stability and
Develop scale-up/scale-down models with attention to equipment
options at various manufacturing facilities.
Collaborating in tech transfer of developed lysis and clarification
processes to manufacturing and supporting implementation.
Plan, coordinate and execute activities for process monitoring and
process data analysis.
Determine root causes of process variation and identify process
trends to increase efficiency.
Effectively organize, interpret, and present data to peers,
cross-functional teams, senior leadership, and colleagues.
Advocate for new bioprocessing and information technologies to help
Required Qualifications and Experience:
Bachelor's degree in Biology, Engineering or related scientific
field with a minimum of 3 years of industry experience. An advanced
degree in a related field may be considered in lieu of
Hands-on experience with industrial methods of cell lysis and
clarification such as centrifugation, depth filtration, and
tangential flow filtration. Experience at multiple scales
Excellent troubleshooting skills and ability to solve complex
Ability to compile, analyze and interpret data.
Communicate effectively across multifunctional teams.
Flexible, adaptable, and desire to take on new technology
challenges and broaden skill set.
Working knowledge of microbial fermentation and protein
New England Biolabs is committed to fostering a diverse and
inclusive community; as an EEO/AA employer, New England Biolabs
considers applicants for employment without regard to, and does not
discriminate on the basis of, race, color, religion, sex, sexual
orientation, gender identity, national origin, protected veteran
status or disability. More in-depth details of EEO are available
Information regarding New England Biolabs commitment to Diversity,
Equity and Inclusion can be found here.
New England Biolabs is a participating employer in the Employment
Verification (E-Verify) program.
OFCCP's pay transparency policy can be found on OFCCP's website at
If you need an accommodation for any part of the employment process
because of a medical condition or disability, please send an email
to firstname.lastname@example.org or call 978-927-5054 to let us know the nature of
Keywords: New England Biolabs, Lynn , Process Development Scientist, Downstream, Other , Ipswich, Massachusetts
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